Kathy McCoy, PhD
Professor, Dept. Of Physiology & Pharmacology, University of Calgary
Scientific Director of the International Microbiome Centre (IMC)
Professor Kathy McCoy obtained her PhD in Immunology from the Malaghan Institute of Medical Research, Otago University, Wellington, New Zealand. She performed her postdoctoral studies and was a junior group leader at the Institute of Experimental Immunology in Zürich, Switzerland. In 2006 she joined McMaster University as an Assistant Professor where she held a Canada Research Chair in Mucosal Immunology. From 2010 – 2016 Kathy McCoy was an Assistant Professor in Mucosal Immunology in the Department of Clinical Research, University of Bern in Switzerland. In Sep 2016 she returned to Canada and is now a Professor in the Cumming School of Medicine, University of Calgary where she continues her research on host-microbial interactions with a focus on early life.
Michael manages the McCoy and Geuking labs. He investigates the role of the microbiome in many different disease states. He performs experiments and helps graduate students, postdoctoral researchers, and staff with their projects while making sure the labs run smoothly. Michael has over 25 years of research experience with the University of Calgary; he started in Neuroscience, investigating stem cell neuroplasticity for several years working with Dr. Sam Weiss, and then worked in the field of inflammation in the gastrointestinal tract with Dr. John Wallace and Dr. Wally MacNaughton before joining the McCoy and Geuking labs.
Christina Ohland, PhD
Dr. Ohland is a Research Associate for the International Microbiome Centre (IMC). She conducts gnotobiotic and microbiome research at the IMC, as well as assisting with funding strategies, training, application development, and technical output from research projects. She received her PhD in Medical Science from the University of Calgary, followed by two postdoctoral fellowships at the University of Alberta and the University of Florida. Her research has spanned the fields of intestinal cell biology, dietary interventions, probiotics, animal behaviour, inflammatory bowel disease, and colorectal cancer. Outside of the lab, Christina enjoys biking, crafting, baking, and playing board games.
Christopher Richmond, MSc
As a laboratory technician, Chris supports our team by providing skilled technical procedures, which include conducting laboratory tests, experiments, and analyses to assist in the goals of the research team on projects for publication. Christopher is a graduate from St. Lawrence College (Kingston, Ontario), the Institute of Technology Sligo (Sligo, Ireland), and Queen’s University (Kingston, Ontario), awarding him an advanced diploma in biotechnology, an honours degree in medical biotechnology, and a masters degree in the field of biochemistry and cellular biology, respectively.
Carolyn Thomson, PhD
Dr. Thomson is a Research Associate in the department of Physiology & Pharmacology and the Snyder Institute of Chronic Diseases at the University of Calgary. Her current research is focused on establishing how maternal colonization impacts immune and metabolomic profiles in the offspring, from early life into adulthood, particularly in the context of autoimmune disease development. Dr. Thomson began her academic career at the University of Glasgow, where she completed a BSc and PhD in Immunology. Her first postdoc position, also at the University of Glasgow, brought her into the field of mucosal immunology. Here she identified and characterized a novel population of intestinal fibroblasts. She is not a fan of work without play. She is an avid gin enthusiast and spends her spare time camping, climbing, and hiking in summer, or shredding the slopes in the harsh Canadian winter.
Aline Ignacio, PhD
Dr. Ignacio is a recipient of an Eyes High Postdoctoral Fellowship. She explores the crosstalk between the intestinal microbiota and mucosal immune cells under homeostatic conditions, which may provide insights into mechanisms responsible for dysregulated immune responses during disease. Dr. Ignacio also studies the early events in microbial-mediated immune education. She obtained her MSc from the University of São Paulo, Brazil, specializing in Microbiology, and her PhD from University of São Paulo, Brazil, specializing in Immunology.
Marcela Davoli Ferreira, PhD
Dr. Ferreira is a recipient of a Beverly Philipps Postdoctoral Fellowship and a Cumming School of Medicine PDF Fellowship. Her research focuses on defining how host-microbiota interactions can promote or prevent autism spectrum disease (ASD). She uses a diverse set of immunological approaches, next-generation sequencing, imaging screening, microbiota cultivation, and gnotobiotic models to further define the molecular mechanisms by which these specific commensals bacteria can influence ASD development. This research aims to develop novel therapeutic interventions for ASD based on the modulation of gut bacteria. Marcela obtained her MSc in Immunology at the University of São Paulo (Brazil). She was awarded a PhD in Immunology from the University of São Paulo where she studied the role of regulatory T cells in the development and maintenance of neuropathic pain after peripheral nerve damage.
Kirsty Brown, PhD
Kirsty has a general interest in how bacteria regulate host physiology, and enjoys applying wet lab techniques and bioinformatics to explore these interests. Her current project investigates how bacterial colonization impacts stromal cell populations in the intestine with a focus on bacteria-induced metabolites. Prior to entering the PhD program at the University of Calgary, Kirsty completed a Master’s degree at the University of British Columbia and worked for a few years at Agriculture and Agri-Food Canada. She also enjoys outdoor activities including hiking, snowboarding, and backcountry camping.
Line Wulff, PhD
Dr. Wulff is a recipient of the Carlberg Foundation Internationalisation Fellowship. Her main research project focuses on the role of intestinal commensal bacteria in trained immunity induction from a data-driven point of view. Dr. Wulff has a background in bioinformatics with a M.Sc.Eng. in Bioinformatics and Systems Biology from the Technical University of Denmark, where she was later awarded a PhD in Mucosal Immunology. During her PhD she specialized in pipeline design and analysis of single cell multi-omics data sets with a special focus human intestinal mononuclear phagocytes.
Pardis Kiani, MSc
Pardis joined Dr. McCoy's lab in September 2022. Pardis holds a Bachelor's degree in Microbiology and has previously earned a Master's degree in Microbial Biotechnology. Driven by a passion for understanding the intricate relationship between microbiota and human health, her current research focus is on unraveling how host-microbiota interactions may play a role in promoting Parkinson's disease. Pardis is excited to be part of the Dr. McCoy team and to collaborate with fellow researchers in exploring innovative solutions to complex scientific questions.
Spencer received his undergraduate degree from Queen’s University in Life Sciences with a specialization in Biomedical Sciences. Before starting his MSc at the University of Calgary, he worked at a small biopharmaceutical company in his hometown in Montréal, acting as a primary coordinator on the microbiology team. These experiences fuelled his passion for investigating how the gut microbiome can be used as means of treating disease. His project is focused investigating how the intestinal microbiome influences type 1 diabetes development by shaping the host immune responses. Spencer is a passionate fan of the Toronto Maple Leafs and hopes to one day see them win the Stanley Cup!
Lukas Mager, PhD
Cancer is one of the most common causes of death in Western countries. Surgery, chemotherapy, radiation, or a combination thereof are the standard tools for the treatment of cancer. More recently, the intestinal microbiota has been shown to modulate cancer development and even affect the efficacy of cancer therapies. Dr. Mager's postdoctoral research aim was to better understand the interaction between the host organism and the microbiota in the context of cancer development and therapy. Besides science, he deeply enjoys being out in nature. One of his favourite hobbies is hiking in mountains. He also enjoys reading and is a fan of strategy games.
Jenine Roslyn Yee, MSc
Jenine was a MSc student in gastrointestinal sciences studying the impact of the gut microbiota on autism spectrum disorder (ASD). She received her nursing degree from University of Calgary before following her unanswered questions about gut health and its resident bacteria. When she isn’t culturing bacteria in lab, she spends time learning piano and cultivating the best tiny potatoes in clay soil.
Noah Cooke, MSc
Noah's MSc project in Gastrointestinal Sciences investigated the potential link between major depressive disorders (MDD) and the microbiome (co-supervised by Dr. Valerie Taylor). Through gut microbial analysis combined with gnotobiotic models, he aimed to further understand the mechanisms by which the gut microbes can impact MDD. Noah is a competitive cross-country skier and runner, and loves the mountains. He also loves politics and public policy.
Nicola Pett, BSc
Nicola was a laboratory technician in our lab. She supported the lab by assisting with experiments, procedures, and general laboratory duties. Nicola obtained her Honours degree in Biomedical Science from the University of Queensland, Australia, where she focused her studies on cell and molecular biology. After gaining experience in the field of cancer immunotherapy, her attention turned to the microbial world of the gastrointestinal tract when she joined the McCoy Lab. Outside of the lab, Nicola enjoys hiking around the Rockies, climbing, and any occasion to be active while enjoying sunlight! She resists the urge to hibernate through winter by learning to snowboard.
Gabriela Quiroz-Olguin, PhD
Gabriela was a PhD student from Mexico. She visited the Geuking and McCoy's lab for 6 months (from Oct 2019 - Mar 2020) to learn microbiome sequencing and IgA-SEQ. While working as a certified dietitian in Mexico City, Gabriela completed a Master’s Degree in Education at the Universidad Tecnológica de Mexico. She then started a PhD in Clinical Nutrition at the Universidad Anahuac in Mexico City, studying the effect of fasting and enteral stimulation on the IgA concentration in saliva of patients pursuing a stomal reversal. Gabriela is a great singer and guitar player. She likes long distant running and has completed several half marathons.
Marcella Cipelli, BSc
Marcella was a visiting PhD student from the University of Sao Paulo, Brazil. She aims to characterize the metabolism of Foxp3+RORgt+ T cells in the context of the colitis-associated colorectal cancer experimental model. To do so, Marcella is standardizing an experimental model, and using in vitro differentiation experiments. She visited our lab for a two month internship to learn about intestinal-associated procedures in animal models.
Amanda Zucoloto, PhD
Amanda was a recipient of the Beverley Phillips Scholarship, the Cumming School of Medicine Scholarship, and the Frederick Banting & Charles Best Canada Graduate Scholarship. Amanda's PhD project aimed to understand the crosstalk between the gut microbiota and the intravascular immunity using intravital microscopy and gnotobiotic models. She obtained her MSc in Experimental Pathology from the Universidade Estadual de Londrina in Londrina, Brazil. During her undergraduate studies, she attended the University of Calgary as a visiting student. Here, Amanda was introduced to intravital microscopy, a cutting-edge technique she aspired to incorporate in her graduate studies. Amanda joined the McCoy and McDonald labs as a PhD student in 2019. In her spare time, Amanda enjoys running, hiking, reading, and camping.
Madeleine Wyss, PhD
Increasing evidence suggests that exposure to a diverse set of ‘friendly’ microbes in early life is important, to prevent the development of allergies. The aim of Madeleine's PhD project was to determine the minimal diversity of microbiota required that limits the induction of hygiene-mediated IgE and protects against immune dysregulation. Furthermore, she was particularly interested in the dynamics of early life microbial colonization and its impacts on immune development. Madeleine completed her BSc at the University of Guelph where she specialized in Microbiology. She then moved to Singapore, where she completed her MSc at the University of Singapore in the Department of Infectious Diseases, Vaccinology and Drug Discovery.
Shannon Pyke, MSc
Shannon's MSc project focused on studying the dynamic function of specific bacterial species in the gut and how they may play a role in anti-microbial resistance. Shannon is from Calgary and completed a Bachelor of Science in Microbiology at the University of Victoria. After graduating, she worked in the biotechnology industry in Vancouver before moving back to Calgary to pursue a Master's degree. In her spare time, she swims competitively and enjoys running, hiking, skiing, and reading.
Sonia Czyz, MSc
Sonia was a Master's student specializing in Microbiology and Infectious Diseases. She obtained her BSc in the Biological Sciences here at the University of Calgary. Having had the opportunity to investigate advanced topics in immunology during her undergraduate studies, she became fascinated with the interplay between the microbiota and the immune system. Her project focused on investigating how the maternal microbiota shapes the newborn’s developing immune system during early-life. Her research aimed to better understand how we can target the maternal microbiome to promote healthy immune development in offspring. Outside of the lab, Sonia enjoys watercolour painting, golf, soccer, and taking her little Yorkshire terrier on long walks.